Advanced Biotech Healiguide Bioresorbable Type I Collagen GTR/GBR Membrane
A sterile, bioresorbable Type I collagen barrier membrane for selected GTR and GBR procedures, available in 15 × 20 mm and 20 × 30 mm sizes.
In selected guided tissue regeneration and guided bone regeneration procedures, a temporary barrier helps separate the regenerative site from rapidly proliferating adjacent soft tissues. Advanced Biotech Healiguide is a sterile, bioresorbable Type I collagen membrane intended for selected periodontal and oral-surgical GTR and GBR procedures.
The membrane is manufactured from high-purity Type I collagen sourced from selected animal tissues. The manufacturer describes the collagen as purified using patented technology, with charge modifications and slight calcification intended to support its role in guided regenerative procedures. The exact animal species is not identified in the available literature and should be confirmed with the manufacturer when required for patient consent, clinical documentation, or individual patient considerations.
Healiguide comes as a thin collagen sheet in a sterile vial. Before placement, it's hydrated in sterile water for approximately one minute, which makes the material pliable enough to trim and adapt to the prepared defect using sterile instruments.
This product listing is available in 15 × 20 mm and 20 × 30 mm sizes. Variant selection should be based on defect dimensions, required coverage, flap design, graft volume, and the planned stabilisation method.
Where clinically indicated, a compatible grafting material can be placed beneath the membrane to support defect management, graft containment, and space maintenance. Healiguide is a barrier membrane rather than a bone-grafting material. It functions as part of the overall regenerative procedure and does not replace a graft where grafting is clinically required.
Because Healiguide is bioresorbable, a separate procedure just to remove the membrane generally isn't needed. That said, the available brochure doesn't specify an exact resorption period or barrier-function duration, so those figures shouldn't be assumed one way or the other.
Healiguide is sterilised using ethylene oxide and intended for single use only — it must not be reused or resterilised, and any unused membrane should be discarded once the vial has been opened. The manufacturer lists active infection, collagen hypersensitivity, and situations where surgery itself is contraindicated among the principal contraindications.
Indications
Suitable for use as part of:
- Guided tissue regeneration in selected periodontal defects
- Guided bone regeneration in selected oral-surgical defects
- Regenerative procedures requiring temporary soft-tissue exclusion
- Periodontal regenerative procedures where a collagen barrier is indicated
- Defect management with a compatible bone-grafting material where required
- Procedures requiring separation of the regenerative site from adjacent soft tissues
Case selection, membrane size, graft selection, fixation, and flap management must be determined by the treating clinician.
- Bioresorbable Type I collagen barrier membrane
- Intended for selected GTR and GBR procedures
- Manufactured from high-purity collagen
- Collagen derived from selected animal tissues
- Thin membrane design for surgical adaptation
- Becomes pliable after hydration
- Can be trimmed according to defect dimensions
- May be stabilised or sutured where clinically required
- Suitable for use with compatible grafting materials when indicated
- Sterilised using ethylene oxide
- Supplied as one sterile membrane in one vial
- Single-use implantable product
- Available in 15 × 20 mm and 20 × 30 mm sizes
- Bioresorbable design generally avoids planned membrane-removal surgery
| Size Variant | Catalogue Number | Packaging |
|---|---|---|
| 15 × 20 mm | 5003.B-1 | 1 sterile membrane in 1 vial |
| 20 × 30 mm | 5003.B-2 | 1 sterile membrane in 1 vial |
| Attribute | Specification |
|---|---|
| Brand | Advanced Biotech |
| Product Name | Healiguide |
| Product Type | Bioresorbable GTR/GBR Membrane |
| Material | Type I Collagen |
| Collagen Source | Selected Animal Tissues |
| Form | Thin Collagen Sheet |
| Available Size Options | 15 × 20 mm and 20 × 30 mm |
| Catalogue Numbers | 5003.B-1 and 5003.B-2 |
| Sterility | Sterile |
| Sterilisation Method | Ethylene Oxide Gas |
| Presentation | 1 Membrane in 1 Vial |
| Hydration | Approximately 1 Minute in Sterile Water |
| Handling After Hydration | Pliable and Trimmable |
| Reuse | Single Use Only |
| Resterilisation | Not Permitted |
| Manufacturer-Stated Shelf Life | 3 Years |
| Storage Range | 4°C to 40°C |
| Intended User | Qualified Dental Professional |
| Supply Status | Prescription Use |
Use only before the expiry date printed on the supplied package. Follow the current Healiguide instructions where they differ from general product information.
- Select the appropriate membrane size according to the defect and planned surgical procedure.
- Check the product expiry date and inspect the vial and outer packaging for damage.
- Do not use the product if the sterile packaging is opened, damaged, or compromised.
- Prepare and debride the surgical site according to the planned GTR or GBR procedure.
- Open the vial using sterile technique and remove the membrane without contaminating it.
- Hydrate the membrane in sterile water for approximately one minute, or as directed in the current Healiguide instructions.
- Once pliable, trim the membrane to the required dimensions using sterile instruments.
- Place a compatible grafting material beneath the membrane where clinically indicated.
- Position the membrane over the prepared defect with appropriate coverage according to the surgical plan.
- Stabilise or suture the membrane when required, using a technique selected by the clinician.
- Confirm that the membrane remains stable and the regenerative site is adequately covered.
- Reposition the flap and achieve appropriate wound closure without excessive compression.
- Discard any unused portion after the vial has been opened.
For professional dental use only.
Clinical Considerations
- Healiguide is intended for single use only.
- Do not reuse or resterilise the membrane.
- Do not place it in an actively infected or contaminated site.
- Do not use in patients with known hypersensitivity to collagen-derived materials.
- Do not use when the planned surgery is medically contraindicated.
- Review the patient's medical history before treatment.
- Assess medicines that may affect surgery or healing, including steroids and anticoagulants.
- Exercise appropriate clinical caution in pregnant patients and children.
- The exact animal species is not stated in the available manufacturer literature.
- Select the membrane size according to defect morphology and required coverage.
- The need for membrane fixation or suturing should be determined according to defect morphology, membrane stability, flap design, and the planned procedure.
- A bone graft is not automatically required in every procedure.
- Avoid excessive compression of the regenerative site.
- The available brochure does not specify the exact resorption period.
- Postoperative hygiene, antimicrobial use, and review intervals should be determined by the treating clinician.
- Advise patients to report severe pain, infection, swelling, sepsis, or excessive bleeding promptly.
Sterility and Handling
- Sterilised using ethylene oxide gas
- Maintain sterile technique during opening and placement
- Do not use if the vial or packaging is damaged
- Do not reuse the membrane
- Do not attempt to resterilise it
- Discard unused material after opening
- Use sterile instruments for hydration, trimming, and placement
- Avoid unnecessary manipulation or contamination
- Keep the membrane in its original sealed packaging until use
| Brand | Advanced Biotech |
|---|
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Variant Price
| Variant | Price |
|---|---|
| Size 15×20 mm | ₹1,515.00 |
| Size 20×30 mm | ₹2,498.00 |
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